Meseclazone

Name: Meseclazone
Brand: TargetMol
SKU: T16353
Rating: 4.5 (1 reviews)

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Catalog No. T16353Cas No. 29053-27-8

Alias W2395, NSC297623

Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.

Meseclazone

😃Good

Catalog No. T16353Alias W2395, NSC297623Cas No. 29053-27-8

Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.
In vivo	Intravenous administration of Meseclazone, along with other nonsteroidal anti-inflammatory drugs (NSAIDs), has been found to cause a dose-dependent reduction in bronchoconstriction. This leads to a sequence of efficacy in decreasing order as follows: isoproterenol ≈ indomethacin > fenoprofen > tolmetin > aspirin > naproxen ≈ ibuprofen > phenylbutazone > diflunisal > Meseclazone > 5-CSA. Additionally, Meseclazone demonstrates the ability to inhibit collagen-induced platelet aggregation 1 and 4 hours post oral administration[1][2].
Synonyms	W2395, NSC297623

Chemical Properties

Molecular Weight	239.65
Formula	C₁₁H₁₀ClNO₃
Cas No.	29053-27-8
Smiles	O=C1N2C(OC=3C1=CC(Cl)=CC3)CC(C)O2
Relative Density.	1.47g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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