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Bidisomide

Name: Bidisomide
Brand: TargetMol
SKU: T12858
Price: 115 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12858Cas No. 116078-65-0

Alias SC40230

Bidisomide (SC40230) is an agent of class I antiarrhythmic.

Bidisomide

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Purity: 99.64%

Catalog No. T12858Alias SC40230Cas No. 116078-65-0

Bidisomide (SC40230) is an agent of class I antiarrhythmic.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$115	In Stock	In Stock
5 mg	$292	In Stock	In Stock
10 mg	$429	In Stock	In Stock
25 mg	$672	In Stock	In Stock
50 mg	$888	In Stock	In Stock
100 mg	$1,180	In Stock	In Stock
500 mg	$2,380	-	In Stock
1 mL x 10 mM (in DMSO)	$322	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.64%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Bidisomide (SC40230) is an agent of class I antiarrhythmic.
In vivo	Bidisomide's anti-arrhythmia effects. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. After 5 minutes of coronary artery occlusion, the antiarrhythmic effect of 5 mg/kg Bidisomide was similar to the same dose of MXT and DSP in rats with ventricular arrhythmias caused by coronary reperfusion. All three drugs significantly slow the heart rate[1].
Synonyms	SC40230

Chemical Properties

Molecular Weight	407.98
Formula	C₂₂H₃₄ClN₃O₂
Cas No.	116078-65-0
Smiles	CC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)C(C)=O
Relative Density.	1.124g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225 mg/mL (551.5 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (12.26 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4511 mL	12.2555 mL	24.5110 mL	122.5550 mL
5 mM	0.4902 mL	2.4511 mL	4.9022 mL	24.5110 mL
10 mM	0.2451 mL	1.2256 mL	2.4511 mL	12.2555 mL
20 mM	0.1226 mL	0.6128 mL	1.2256 mL	6.1278 mL
50 mM	0.0490 mL	0.2451 mL	0.4902 mL	2.4511 mL
100 mM	0.0245 mL	0.1226 mL	0.2451 mL	1.2256 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc