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BI-765063 (OSE-172) is a sophisticated humanized IgG4 monoclonal antibody function as a selective antagonist of the signal-regulatory protein α (SIRP α), reactivation of macrophage-mediated phagocytosis by specifically disrupting the inhibitory CD47/SIRP α signaling axis within the tumor microenvironment.

| Description | BI-765063 (OSE-172) is a sophisticated humanized IgG4 monoclonal antibody function as a selective antagonist of the signal-regulatory protein α (SIRP α), reactivation of macrophage-mediated phagocytosis by specifically disrupting the inhibitory CD47/SIRP α signaling axis within the tumor microenvironment. |
| Synonyms | OSE-172 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | SIRPa/CD172a |
| Isotype | IgG4PE |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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