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L-Ascorbic Acid 6-stearate

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Catalog No. T83876Cas No. 10605-09-1
Alias L-Ascorbyl-6-stearate, 6-O-Stearoyl-L-Ascorbic Acid

L-Ascorbic acid 6-stearate, a compound derived from L-ascorbic acid and stearic acid identified in K. coccinea, exhibits antioxidant and anticancer properties. It effectively scavenges DPPH radicals in cell-free assays (IC50 = 3.31 µg/ml). Additionally, lipid nanoparticles (LNPs) containing L-ascorbic acid 6-stearate have been shown to trigger apoptosis in HL-60 promyeloblasts at a concentration of 190 µM. This compound is also incorporated into cosmetic and personal care product formulations due to its beneficial effects.

L-Ascorbic Acid 6-stearate

L-Ascorbic Acid 6-stearate

😃Good
Catalog No. T83876Alias L-Ascorbyl-6-stearate, 6-O-Stearoyl-L-Ascorbic AcidCas No. 10605-09-1
L-Ascorbic acid 6-stearate, a compound derived from L-ascorbic acid and stearic acid identified in K. coccinea, exhibits antioxidant and anticancer properties. It effectively scavenges DPPH radicals in cell-free assays (IC50 = 3.31 µg/ml). Additionally, lipid nanoparticles (LNPs) containing L-ascorbic acid 6-stearate have been shown to trigger apoptosis in HL-60 promyeloblasts at a concentration of 190 µM. This compound is also incorporated into cosmetic and personal care product formulations due to its beneficial effects.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$17835 days35 days
250 mg$39735 days35 days
500 mg$67835 days35 days
1 g$81935 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Product Introduction

Bioactivity
Description
L-Ascorbic acid 6-stearate, a compound derived from L-ascorbic acid and stearic acid identified in K. coccinea, exhibits antioxidant and anticancer properties. It effectively scavenges DPPH radicals in cell-free assays (IC50 = 3.31 µg/ml). Additionally, lipid nanoparticles (LNPs) containing L-ascorbic acid 6-stearate have been shown to trigger apoptosis in HL-60 promyeloblasts at a concentration of 190 µM. This compound is also incorporated into cosmetic and personal care product formulations due to its beneficial effects.
SynonymsL-Ascorbyl-6-stearate, 6-O-Stearoyl-L-Ascorbic Acid
Chemical Properties
Molecular Weight442.60
FormulaC24H42O7
Cas No.10605-09-1
SmilesCCCCCCCCCCCCCCCCCC(=O)OCC(O)C1OC(O)=C(O)C1=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 5 mg/mL (11.3 mM), Sonication is recommended.
DMF: 10 mg/mL (22.59 mM), Sonication is recommended.
DMSO: 10 mg/mL (22.59 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMF/DMSO
1mg5mg10mg50mg
1 mM2.2594 mL11.2969 mL22.5938 mL112.9688 mL
5 mM0.4519 mL2.2594 mL4.5188 mL22.5938 mL
10 mM0.2259 mL1.1297 mL2.2594 mL11.2969 mL
DMF/DMSO
1mg5mg10mg50mg
20 mM0.1130 mL0.5648 mL1.1297 mL5.6484 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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