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Leucomycin a5

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Catalog No. T32669Cas No. 18361-45-0
Alias Turimycin H4, Leukomycin A5

Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 µg/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 µg/ml, respectively) and S. faecalis (MIC = 0.8 µg/ml).

Leucomycin a5

Leucomycin a5

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Catalog No. T32669Alias Turimycin H4, Leukomycin A5Cas No. 18361-45-0
Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 µg/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 µg/ml, respectively) and S. faecalis (MIC = 0.8 µg/ml).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$44535 days35 days
5 mg$1,98035 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 µg/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 µg/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 µg/ml, respectively) and S. faecalis (MIC = 0.8 µg/ml).
SynonymsTurimycin H4, Leukomycin A5
Chemical Properties
Molecular Weight771.93
FormulaC39H65NO14
Cas No.18361-45-0
Smiles[H][C@@]1(C[C@@](C)(O)[C@@H](OC(=O)CCC)[C@H](C)O1)O[C@@H]1[C@@H](C)O[C@@]([H])(O[C@H]2[C@@H](CC=O)C[C@@H](C)[C@@H](O)\C=C\C=C\C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]2OC)[C@H](O)[C@H]1N(C)C
Relative Density.1.22 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Leucomycin a-5Leucomycin a5
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