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5'-O-TBDMS-dG

Name: 5'-O-TBDMS-dG
Brand: TargetMol
SKU: T37144
Rating: 4.5 (1 reviews)

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Catalog No. T37144Cas No. 51549-33-8

5'-O-TBDMS-dG is a modified nucleoside, while 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.

5'-O-TBDMS-dG

😃Good

Catalog No. T37144Cas No. 51549-33-8

5'-O-TBDMS-dG is a modified nucleoside, while 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.

Pack Size	Price	Availability	Quantity
50 mg	$42	Backorder
1 mL x 10 mM (in DMSO)	$46	Backorder

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Product Introduction

Bioactivity

Description

5'-O-TBDMS-dG is a modified nucleoside, while 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.

Chemical Properties

Molecular Weight	381.50
Formula	C₁₆H₂₇N₅O₄Si
Cas No.	51549-33-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250.00 mg/mL (655.31 mM), Sonication and heating to 60℃ are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6212 mL	13.1062 mL	26.2123 mL	131.0616 mL
5 mM	0.5242 mL	2.6212 mL	5.2425 mL	26.2123 mL
10 mM	0.2621 mL	1.3106 mL	2.6212 mL	13.1062 mL
20 mM	0.1311 mL	0.6553 mL	1.3106 mL	6.5531 mL
50 mM	0.0524 mL	0.2621 mL	0.5242 mL	2.6212 mL
100 mM	0.0262 mL	0.1311 mL	0.2621 mL	1.3106 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc