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Vitamin E succinate

Name: Vitamin E succinate
Brand: TargetMol
SKU: T64914
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T64914Cas No. 4345-03-3

Alias D-α-Tocopherol Succinate

Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.

Vitamin E succinate

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Purity: 99.24%

Catalog No. T64914Alias D-α-Tocopherol SuccinateCas No. 4345-03-3

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$30	In Stock	In Stock
100 mg	$40	In Stock	In Stock
500 mg	$77	In Stock	In Stock
1 g	$113	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.24%

Appearance:Solid

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.
In vitro	In the HEI-OC1 cell line,Vitamin E succinate (1-20 μM; 24 hours) significantly induced cytotoxicity at a concentration of 20 μM and showed a higher cytotoxic potency compared to 10 μM[1].
In vivo	In female C57BL/6 mice aged 6-8 weeks with TC-1 tumor cells,Vitamin E succinate (2 mg/kg; intraperitoneal injection; three times every 2 days, starting from the injection of TC-1 tumor cells and continuing for 10 to 14 days) decreased tumor volume[2].
Synonyms	D-α-Tocopherol Succinate

Chemical Properties

Molecular Weight	530.78
Formula	C₃₃H₅₄O₅
Cas No.	4345-03-3
Smiles	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 120 mg/mL (226.08 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8840 mL	9.4201 mL	18.8402 mL	94.2010 mL
5 mM	0.3768 mL	1.8840 mL	3.7680 mL	18.8402 mL
10 mM	0.1884 mL	0.9420 mL	1.8840 mL	9.4201 mL
20 mM	0.0942 mL	0.4710 mL	0.9420 mL	4.7100 mL
50 mM	0.0377 mL	0.1884 mL	0.3768 mL	1.8840 mL
100 mM	0.0188 mL	0.0942 mL	0.1884 mL	0.9420 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc