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Vitamin E succinate

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Catalog No. T64914Cas No. 4345-03-3
Alias D-α-Tocopherol Succinate

Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.

Vitamin E succinate

Vitamin E succinate

🥰Excellent
Purity: 99.24%
Catalog No. T64914Alias D-α-Tocopherol SuccinateCas No. 4345-03-3
Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$30In StockIn Stock
100 mg$40In StockIn Stock
500 mg$77In StockIn Stock
1 g$113In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.24%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.
In vitro
In the HEI-OC1 cell line,Vitamin E succinate (1-20 μM; 24 hours) significantly induced cytotoxicity at a concentration of 20 μM and showed a higher cytotoxic potency compared to 10 μM[1].
In vivo
In female C57BL/6 mice aged 6-8 weeks with TC-1 tumor cells,Vitamin E succinate (2 mg/kg; intraperitoneal injection; three times every 2 days, starting from the injection of TC-1 tumor cells and continuing for 10 to 14 days) decreased tumor volume[2].
SynonymsD-α-Tocopherol Succinate
Chemical Properties
Molecular Weight530.78
FormulaC33H54O5
Cas No.4345-03-3
SmilesCC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(=O)CCC(O)=O)c(C)c(C)c2O1
ColorPink
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 120 mg/mL (226.08 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8840 mL9.4201 mL18.8402 mL94.2010 mL
5 mM0.3768 mL1.8840 mL3.7680 mL18.8402 mL
10 mM0.1884 mL0.9420 mL1.8840 mL9.4201 mL
20 mM0.0942 mL0.4710 mL0.9420 mL4.7100 mL
50 mM0.0377 mL0.1884 mL0.3768 mL1.8840 mL
100 mM0.0188 mL0.0942 mL0.1884 mL0.9420 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Apoptosis
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