Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 430.00 | |
10 mg | In stock | $ 636.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 | |
100 mg | In stock | $ 1,830.00 | |
500 mg | In stock | $ 3,680.00 |
Description | 2-Hydroxy-3-methoxy chalcone has anticancer activity and inhibits colon cancer. |
Targets&IC50 | mTOR:21 µM |
In vitro | 2'-hydroxy-3'-methoxychalcone (TJ3) (10 µM and 25 µM ) significantly reduced the release of ICAM-1 by SW480 cancer cells. It did not have a significant effect on VCAM-1 released by SW480 and SW620 cancer cell lines. However, it demonstrated a significant dose-dependent reduction in the concentration of MIF on SW480 cells. Additionally, TJ3 at a concentration of 25 µM significantly decreased IL-8 secretion by both SW480 and SW620 cancer cells. These results indicate that the tested TJ3 exhibits a modulating effect on colon cancer cells.[1] |
Molecular Weight | 254.28 |
Formula | C16H14O3 |
CAS No. | 7146-86-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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2-Hydroxy-3-methoxy chalcone 7146-86-3 inhibitor inhibit