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Adrenochrome

Name: Adrenochrome
Brand: TargetMol
SKU: T20094
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20094Cas No. 54-06-8

Alias Adraxone

Adrenochrome (Adraxone) is a cytotoxic molecule that can be used to kill bacteria. Adrenochrome is an oxidized product of Epinephrine. Adrenochrome is a coronary systolic compound that acts on rat hearts and is associated with cardiotoxicity and can be used to determine superoxide dismutase activity. Adrenochrome is a potential psychotropic drug for the study of nervous system diseases.

Adrenochrome

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Purity: 99.86%

Catalog No. T20094Alias AdraxoneCas No. 54-06-8

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$30	-	In Stock
5 mg	$42	-	In Stock
10 mg	$68	-	In Stock
25 mg	$109	-	In Stock
50 mg	$158	-	In Stock
100 mg	$233	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.86%

Appearance:Solid

Color:Black

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Adrenochrome (Adraxone) is a cytotoxic molecule that can be used to kill bacteria. Adrenochrome is an oxidized product of Epinephrine. Adrenochrome is a coronary systolic compound that acts on rat hearts and is associated with cardiotoxicity and can be used to determine superoxide dismutase activity. Adrenochrome is a potential psychotropic drug for the study of nervous system diseases.
In vitro	Microsomal calcium binding, calcium uptake, and Ca2+-stimulated Mg2+-dependent ATPase activities are reduced in the presence of Adrenochrome. The inhibitory impact of Adrenochrome on microsomal calcium uptake activity of the isolated membrane remains unaffected by various factors, including pH (ranging from 6.0 to 8.0), calcium concentrations (ranging from 10 to 200 μM), protein concentration (ranging from 0.02 to 0.10 mg/mL), temperature (ranging from 25 to 37 degrees C), and incubation time (ranging from 2 to 30 minutes). [1]
In vivo	In isolated rat hearts, the administration of Adrenochrome at concentrations ranging from 1 to 1000 ng/mL leads to a dose- and time-dependent elevation in coronary pressure. Moreover, the extent of constriction induced by Adrenochrome is influenced by the concentration of CaCl2 in the perfusion medium. [2]
Synonyms	Adraxone

Chemical Properties

Molecular Weight	179.17
Formula	C₉H₉NO₃
Cas No.	54-06-8
Smiles	OC1C=2C(N(C)C1)=CC(=O)C(=O)C2
Relative Density.	1.2822 g/cm3 (Estimated)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (502.32 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.5813 mL	27.9065 mL	55.8129 mL	279.0646 mL
5 mM	1.1163 mL	5.5813 mL	11.1626 mL	55.8129 mL
10 mM	0.5581 mL	2.7906 mL	5.5813 mL	27.9065 mL
20 mM	0.2791 mL	1.3953 mL	2.7906 mL	13.9532 mL
50 mM	0.1116 mL	0.5581 mL	1.1163 mL	5.5813 mL
100 mM	0.0558 mL	0.2791 mL	0.5581 mL	2.7906 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc