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Nebivolol
🥰Excellent
Catalog No. T21426Cas No. 118457-14-0
Alias Vasoxen, R-065824, R065824, R 065824, Nobiten
Nebivolol, a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect, is used in treatment of hypertension, in Europe, it is also used for left ventricular failure. It is highly cardioselective under certain circumstances.
Nebivolol
🥰Excellent
Catalog No. T21426Alias Vasoxen, R-065824, R065824, R 065824, NobitenCas No. 118457-14-0
Nebivolol, a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect, is used in treatment of hypertension, in Europe, it is also used for left ventricular failure. It is highly cardioselective under certain circumstances.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Nebivolol, a β1 receptor blocker with nitric oxide-potentiating vasodilatory effect, is used in treatment of hypertension, in Europe, it is also used for left ventricular failure. It is highly cardioselective under certain circumstances. |
| Synonyms | Vasoxen, R-065824, R065824, R 065824, Nobiten |
| Molecular Weight | 405.44 |
| Formula | C22H25F2NO4 |
| Cas No. | 118457-14-0 |
| Smiles | [C@@H](CNC[C@H](O)[C@]1(OC=2C(CC1)=CC(F)=CC2)[H])(O)[C@@]3(OC=4C(CC3)=CC(F)=CC4)[H] |
| Relative Density. | 1.309 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: Insoluble DMSO: Soluble |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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