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Turbinaric acid
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Catalog No. T13946Cas No. 56882-00-9
Turbinaric acid is a moderately cytotoxic squalene carboxylic acid isolated from brown algae (Turbinaria ornata).
Turbinaric acid
😃Good
Purity: 99.62%
Catalog No. T13946Cas No. 56882-00-9
Turbinaric acid is a moderately cytotoxic squalene carboxylic acid isolated from brown algae (Turbinaria ornata).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $71 | - | In Stock | |
| 5 mg | $172 | - | In Stock | |
| 10 mg | $289 | - | In Stock | |
| 25 mg | $587 | - | In Stock | |
| 50 mg | $848 | - | In Stock | |
| 100 mg | $1,190 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.62%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Turbinaric acid is a moderately cytotoxic squalene carboxylic acid isolated from brown algae (Turbinaria ornata). |
| In vitro | Methods: Peripheral blood mononuclear cells containing NK cells were isolated and cocultured with target K562 cells at three different effector-to-target (E:T) ratios of 50:1, 25:1, and 12.5:1. Prednisolone hemisuccinate or IVIG were then added to the tubes at an E:T ratio of 50:1 to assess the inhibitory effect. Percent killing was recorded and statistically analyzed using the Student t test. Results: In experiments with an E:T ratio of 50:1 and either Prednisolone hemisuccinate or IVIG in the coculture, the mean target cell killing rate was 26.4%. In cultures using the same E:T ratio, this killing rate was significantly reduced in the presence of IVIG (9.9%) or Prednisolone hemisuccinate (13.6%) (P < 0.001 for both analyses). Prednisolone hemisuccinate was able to inhibit the cytolytic activity of NK cells. [1] |
| Molecular Weight | 400.64 |
| Formula | C27H44O2 |
| Cas No. | 56882-00-9 |
| Smiles | CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C=C(/C)CC\C=C(/C)CCC(O)=O |
| Relative Density. | 0.919g/cm3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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