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Synonyms:


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $68 | - | In Stock | |
| 5 mg | $149 | - | In Stock | |
| 10 mg | $232 | - | In Stock | |
| 25 mg | $464 | - | In Stock | |
| 50 mg | $696 | - | In Stock | |
| 100 mg | $1,040 | - | In Stock |
| Description | HOR1-C59 is a highly selective and potent Or5v1/Olfr110 agonist with an EC50 of 7.12 nM; it is a non-natural synthetic small molecule. HOR1-C59 improves glucose homeostasis and alleviates obesity and insulin resistance. HOR1-C59 can be used in research on obesity and metabolic diseases. |
| In vivo | Intraperitoneal injection of HOR1-C59 (50 ng/g, administered daily) for 8 weeks improved glucose metabolism and alleviated obesity symptoms in wild-type mice fed a high-fat diet (HFD), but this effect was not observed in Olfr110 knockout mice.[1] |
| Molecular Weight | 368.43 |
| Formula | C21H24N2O4 |
| Cas No. | 189574-20-7 |
| Smiles | C(NCC1=CC=CC=C1)(=O)[C@H]2[C@H](C(NCC3=CC=CC=C3)=O)OC(C)(C)O2 |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 µL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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