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11β-Hydroxyandrosterone

Name: 11β-Hydroxyandrosterone
Brand: TargetMol
SKU: T73780
Rating: 4.5 (1 reviews)

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Catalog No. T73780Cas No. 57-61-4

11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.

11β-Hydroxyandrosterone

😃Good

Catalog No. T73780Cas No. 57-61-4

11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$149	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	11β-Hydroxyandrosterone is a urinary adrenal-derived androgen metabolite in children with CAH.
In vitro	Among the metabolites of DHEA, AD4, and 11OHAD4, only 11β-Hydroxyandrosterone (a metabolite of 11OHAD4) showed no overlap between C21OHD (classic 21-hydroxylase deficiency) and PORD (cytochrome P450 oxidoreductase deficiency) at a threshold of 0.35 mg/g creatinine. Detection of 11β-Hydroxyandrosterone distinguished the two. [1]

Chemical Properties

Molecular Weight	306.44
Formula	C₁₉H₃₀O₃
Cas No.	57-61-4
Smiles	C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)C(=O)CC4)[H])(CC[C@]1(C[C@H](O)CC2)[H])[H])[H]

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (261.06 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2633 mL	16.3164 mL	32.6328 mL	163.1641 mL
5 mM	0.6527 mL	3.2633 mL	6.5266 mL	32.6328 mL
10 mM	0.3263 mL	1.6316 mL	3.2633 mL	16.3164 mL
20 mM	0.1632 mL	0.8158 mL	1.6316 mL	8.1582 mL
50 mM	0.0653 mL	0.3263 mL	0.6527 mL	3.2633 mL
100 mM	0.0326 mL	0.1632 mL	0.3263 mL	1.6316 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc