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Amlenetug
(Synonyms: Lu-AF82422) Copy Product Info
🥰Excellent
Synonyms: Lu-AF82422
Catalog No. T9901A-460 Copy Product Info
Purity: 95%
🥰Excellent
Amlenetug (Lu AF82422) is a human monoclonal antibody targeting α-synuclein that is in development for multiple system atrophy, demonstrating robust inhibition of α-synuclein seeding induced by diverse fibrillar assemblies in mouse primary neurons and by aggregates derived from MSA brain homogenates, while in vivo studies show that both intracerebral co-injection and peripheral administration effectively suppress α-synuclein seeding and pathological propagation.
Amlenetug
Cas No. 2850367-41-6
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $232 | - | In Stock | |
| 5 mg | $697 | - | In Stock | |
| 10 mg | $1,050 | - | In Stock | |
| 25 mg | $1,790 | - | In Stock | |
| 50 mg | $2,690 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95%
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Amlenetug (Lu AF82422) is a human monoclonal antibody targeting α-synuclein that is in development for multiple system atrophy, demonstrating robust inhibition of α-synuclein seeding induced by diverse fibrillar assemblies in mouse primary neurons and by aggregates derived from MSA brain homogenates, while in vivo studies show that both intracerebral co-injection and peripheral administration effectively suppress α-synuclein seeding and pathological propagation. |
| Synonyms | Lu-AF82422 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Alpha-synuclein Protein (His) (TMPJ-00023) at 1 μg/mL (100 μL/well) can bind Amlenetug. The EC50 is 1.48 ng/mL.  |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Cas No. | 2850367-41-6 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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