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Hericenone C
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Catalog No. TN8546Cas No. 137592-03-1
Hericenone C (Hericium erinaceus ketone C) is a natural product and α-glucosidase inhibitor, which can be used for biochemical experiments and drug synthesis.
Hericenone C
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Catalog No. TN8546Cas No. 137592-03-1
Hericenone C (Hericium erinaceus ketone C) is a natural product and α-glucosidase inhibitor, which can be used for biochemical experiments and drug synthesis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 7-10 days | 7-10 days | |
| 50 mg | Inquiry | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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| Description | Hericenone C (Hericium erinaceus ketone C) is a natural product and α-glucosidase inhibitor, which can be used for biochemical experiments and drug synthesis. |
| In vitro | Methods: RAW264.7 cells were treated with Hericenone C (40 μM, before formalin administration) to investigate the role of Hericenone C in formalin-induced nociceptive behavior. Results: Formalin induced the mRNA expression of the inflammatory cytokine Il-6, while Hericenone C significantly inhibited its expression. [1] |
| In vivo | Methods: The antinociceptive effect of Hericenone C was evaluated by intraperitoneal injection (2.5, 5, 10 mg/kg, before formalin injection). Results: Hericenone C pretreatment inhibited the total duration of pain-related behaviors in the second phase of formalin-induced nociception in a dose-dependent manner and showed a significant effect. [1] |
| Molecular Weight | 570.8 |
| Formula | C35H54O6 |
| Cas No. | 137592-03-1 |
| Smiles | C(/C=C(/CC(C=C(C)C)=O)\C)C1=C(OC)C=C(COC(CCCCCCCCCCCCCCC)=O)C(C=O)=C1O |
| Storage | keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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