Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

4-(Trifluoromethyl)umbelliferone

Catalog No. Fr13444 Copy Product Info
Purity: 99.14%
🥰Excellent
4-(Trifluoromethyl)umbelliferone is a coumarin-derived fluorescent compound substituted with a trifluoromethyl group. 4-(Trifluoromethyl)umbelliferone exhibits pH-responsive fluorescence, high quantum yield, metabolic stability, and enzyme substrate specificity, making it a versatile fluorescent probe for biomedical research. 4-(Trifluoromethyl)umbelliferone can be used for the detection of cytochrome P450 enzyme and UDP-glucuronosyltransferase activity, as well as for pH indication applications.

4-(Trifluoromethyl)umbelliferone

Copy Product Info
🥰Excellent
Catalog No. Fr13444

4-(Trifluoromethyl)umbelliferone is a coumarin-derived fluorescent compound substituted with a trifluoromethyl group. 4-(Trifluoromethyl)umbelliferone exhibits pH-responsive fluorescence, high quantum yield, metabolic stability, and enzyme substrate specificity, making it a versatile fluorescent probe for biomedical research. 4-(Trifluoromethyl)umbelliferone can be used for the detection of cytochrome P450 enzyme and UDP-glucuronosyltransferase activity, as well as for pH indication applications.

4-(Trifluoromethyl)umbelliferone
Cas No. 575-03-1
Pack SizePriceUSA StockGlobal StockQuantity
500 mg$29-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.14%
Appearance:Solid
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
4-(Trifluoromethyl)umbelliferone is a coumarin-derived fluorescent compound substituted with a trifluoromethyl group. 4-(Trifluoromethyl)umbelliferone exhibits pH-responsive fluorescence, high quantum yield, metabolic stability, and enzyme substrate specificity, making it a versatile fluorescent probe for biomedical research. 4-(Trifluoromethyl)umbelliferone can be used for the detection of cytochrome P450 enzyme and UDP-glucuronosyltransferase activity, as well as for pH indication applications.
Chemical Properties
Molecular Weight230.14
FormulaC10H5F3O3
Cas No.575-03-1
SmilesO=C1OC=2C=C(O)C=CC2C(=C1)C(F)(F)F
Relative Density.1.569 g/cm3
Storage & Solubility Information
StorageStore at -20°C Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (347.61 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3452 mL21.7259 mL43.4518 mL217.2591 mL
5 mM0.8690 mL4.3452 mL8.6904 mL43.4518 mL
10 mM0.4345 mL2.1726 mL4.3452 mL21.7259 mL
20 mM0.2173 mL1.0863 mL2.1726 mL10.8630 mL
50 mM0.0869 mL0.4345 mL0.8690 mL4.3452 mL
100 mM0.0435 mL0.2173 mL0.4345 mL2.1726 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Compound Fr13444
Related Tags: buy 4-(Trifluoromethyl)umbelliferone | purchase 4-(Trifluoromethyl)umbelliferone | 4-(Trifluoromethyl)umbelliferone cost | order 4-(Trifluoromethyl)umbelliferone | 4-(Trifluoromethyl)umbelliferone chemical structure | 4-(Trifluoromethyl)umbelliferone formula | 4-(Trifluoromethyl)umbelliferone molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.