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Etersalate

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Catalog No. T15252Cas No. 62992-61-4
Alias Etherylate, Eterylate

Etersalate inhibits platelet function. It also reduces thromboxane A2 (TXA2) levels.

Etersalate

Etersalate

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Catalog No. T15252Alias Etherylate, EterylateCas No. 62992-61-4
Etersalate inhibits platelet function. It also reduces thromboxane A2 (TXA2) levels.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5206-8 weeks6-8 weeks
50 mg$1,9806-8 weeks6-8 weeks
100 mg$2,5006-8 weeks6-8 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Etersalate inhibits platelet function. It also reduces thromboxane A2 (TXA2) levels.
In vitro
Etersalate, at lower doses, both inhibits platelet function and reduces thromboxane A2 (TXA2) levels, while simultaneously stimulating prostaglandin I2 (PGI2) generation in aortic rings from rats treated with plasma from Etersalate-administered donors. Blood coagulation metrics remain unaffected. The study explores Etersalate's ex vivo antiplatelet effects and its influence on serum TXA2 levels and PGI2 production in human volunteers across two dosages. Distinctively, Etersalate impacts platelet arachidonate metabolism through a mechanism separate from the cyclooxygenase pathway.
SynonymsEtherylate, Eterylate
Chemical Properties
Molecular Weight357.36
FormulaC19H19NO6
Cas No.62992-61-4
SmilesO(C(C)=O)C1=C(C(OCCOC2=CC=C(NC(C)=O)C=C2)=O)C=CC=C1
Relative Density.1.263 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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