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RCD405 is a bronchodilator that exerts a relaxing effect by directly acting on human airway smooth muscle (hASM), with an EC50 value of 12 μM for histamine-induced contraction and 45.71 μM for carbachol-induced contraction. It inhibits cholinergic and histaminergic tension and reduces contractions induced by electrical field stimulation (EFS). RCD405 shows potential for research in asthma and chronic obstructive pulmonary disease (COPD).

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks | 10-14 weeks |
| Description | RCD405 is a bronchodilator that exerts a relaxing effect by directly acting on human airway smooth muscle (hASM), with an EC50 value of 12 μM for histamine-induced contraction and 45.71 μM for carbachol-induced contraction. It inhibits cholinergic and histaminergic tension and reduces contractions induced by electrical field stimulation (EFS). RCD405 shows potential for research in asthma and chronic obstructive pulmonary disease (COPD). |
| Molecular Weight | 453.26 |
| Formula | C17H13Cl2F3N2O3S |
| Cas No. | 2408134-22-3 |
| Smiles | O=C(N1CC2=C(Cl)C(O)=C(O)C(Cl)=C2CC1)CSC3=CN=C(C=C3)C(F)(F)F |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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