Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening.
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Description | VU661, a redox-active phenazine carboxamide, modulates circadian rhythms by inducing period lengthening. |
In vitro | VU661, at concentrations of 1, 3, and 10 μM over a period of 0 to 144 hours, exhibits a dose-dependent prolongation effect (extending the period by 7.2 hours at 10 μM), with minimal impact on the amplitude of Bmal1-dLuc U2OS cells [1]. Additionally, VU661, at 1 and 10 μM for 24 hours, increases the cellular optical redox ratio in a dose-dependent manner [1]. There is negligible effect on cellular ROS or hydrogen peroxide levels by VU661 [1]. |
Molecular Weight | 299.33 |
Formula | C19H13N3O |
CAS No. | 37648-76-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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VU661 37648-76-3 inhibitor inhibit