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Anti-HER3/ERBB3 Antibody (2V371)
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Catalog No. TMAY-00453
Alias erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody (2V371) is a Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (2V371) can be used in ELISA.
Anti-HER3/ERBB3 Antibody (2V371)
Anti-HER3/ERBB3 Antibody (2V371)
😃Good
Catalog No. TMAY-00453Alias erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody (2V371) is a Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (2V371) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-HER3/ERBB3 Antibody (2V371) is a Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody (2V371) can be used in ELISA. |
| Alias | erb-b2 receptor tyrosine kinase 3 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2V371 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human HER3 / ErbB3 (rh HER3 / ErbB3; TMPY-01389; Met 1-Thr 643; NP_001973.2) . |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human HER3 / ErbB3 Protein (TMPY-01389) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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