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Acetoacetyl Coenzyme A sodium hydrate

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Catalog No. T36827
Alias Acetoacetyl-CoA sodium hydrate

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Acetoacetyl Coenzyme A sodium hydrate
Other Forms of Acetoacetyl Coenzyme A sodium hydrate:

Acetoacetyl Coenzyme A sodium hydrate

😃Good
Catalog No. T36827Alias Acetoacetyl-CoA sodium hydrate
Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.
Pack SizePriceAvailabilityQuantity
1 mg$339In Stock
5 mg$1,180Backorder
10 mg$1,898Backorder
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Product Introduction

Bioactivity
Description
Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.
Targets&IC50
Acetate:0.021 mM (Km), Butyrate:0.056 mM (Km), Propionate:0.007 mM (Km)
In vitro
Km values for Acetoacetyl Coenzyme A sodium hydrate, acetate, and propionate were calculated from intercept and slope replots. The Km, values for Acetoacetyl Coenzyme A the acetate as substrate were 0.021 mM. The Km, values for Acetoacetyl Coenzyme A the propionate as substrate were 0.007 mM. The Km, values for Acetoacetyl Coenzyme A the butyrate as substrate were 0.056 mM. The Km, values for the carboxylic acids were remarkably high. [1]
SynonymsAcetoacetyl-CoA sodium hydrate
Chemical Properties
Molecular Weight989.61
FormulaC25H45N7Na3O22P3S
SmilesO[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)([O-])=O)COP(OP(OCC(C)([C@H](C(NCCC(NCCSC(CC(C)=O)=O)=O)=O)O)C)([O-])=O)([O-])=O)N2C=NC3=C2N=CN=C3N.[Na+].[Na+].[Na+].O.O.O.O
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 8 mg/mL (8.53 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (10.1 mM), Sonication is recommended.
Solution Preparation Table
H2O/PBS (pH 7.2)
1mg5mg10mg50mg
1 mM1.0105 mL5.0525 mL10.1050 mL50.5250 mL
5 mM0.2021 mL1.0105 mL2.0210 mL10.1050 mL
PBS (pH 7.2)
1mg5mg10mg50mg
10 mM0.1010 mL0.5052 mL1.0105 mL5.0525 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

sodium HydrateAcetoacetyl-CoAAcetoacetyl Coenzyme A (sodium salt hydrate)Acetoacetyl Coenzyme A
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