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Acetoacetyl Coenzyme A sodium hydrate

Name: Acetoacetyl Coenzyme A sodium hydrate
Brand: TargetMol
SKU: T36827
Price: 198 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T36827

Alias Acetoacetyl-CoA sodium hydrate

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Acetoacetyl Coenzyme A sodium hydrate

Copy Product Info

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Catalog No. T36827Alias Acetoacetyl-CoA sodium hydrate

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mg	$198	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.
Targets&IC50	Acetate:0.021 mM (Km), Butyrate:0.056 mM (Km), Propionate:0.007 mM (Km)
In vitro	Km values for Acetoacetyl Coenzyme A sodium hydrate, acetate, and propionate were calculated from intercept and slope replots. The Km, values for Acetoacetyl Coenzyme A the acetate as substrate were 0.021 mM. The Km, values for Acetoacetyl Coenzyme A the propionate as substrate were 0.007 mM. The Km, values for Acetoacetyl Coenzyme A the butyrate as substrate were 0.056 mM. The Km, values for the carboxylic acids were remarkably high. [1]
Synonyms	Acetoacetyl-CoA sodium hydrate

Chemical Properties

Molecular Weight	989.61
Formula	C₂₅H₄₅N₇Na₃O₂₂P₃S
Smiles	O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)([O-])=O)COP(OP(OCC(C)([C@H](C(NCCC(NCCSC(CC(C)=O)=O)=O)=O)O)C)([O-])=O)([O-])=O)N2C=NC3=C2N=CN=C3N.[Na+].[Na+].[Na+].O.O.O.O

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 8 mg/mL (8.08 mM), Sonication is recommended.

PBS (pH 7.2): 10 mg/mL (10.1 mM), Sonication is recommended.

Solution Preparation Table

H2O/PBS (pH 7.2)

	1mg	5mg	10mg	50mg
1 mM	1.0105 mL	5.0525 mL	10.1050 mL	50.5250 mL
5 mM	0.2021 mL	1.0105 mL	2.0210 mL	10.1050 mL

PBS (pH 7.2)

	1mg	5mg	10mg	50mg
10 mM	0.1010 mL	0.5052 mL	1.0105 mL	5.0525 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

sodium HydrateAcetoacetyl-CoAAcetoacetyl Coenzyme A (sodium salt hydrate)Acetoacetyl Coenzyme A

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