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C5 Lenalidomide

Name: C5 Lenalidomide
Brand: TargetMol
SKU: T9270
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9270Cas No. 191732-70-4

C5 Lenalidomide is an chemical weith inconclusive biological activity.

C5 Lenalidomide

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🥰Excellent

Purity: 99.4%

Catalog No. T9270Cas No. 191732-70-4

C5 Lenalidomide is an chemical weith inconclusive biological activity.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$33	In Stock	In Stock
50 mg	Preferential	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.4%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

C5 Lenalidomide AI Summary

C5 Lenalidomide exhibits significant bioactivities, including anti-inflammatory activity in human peripheral blood mononuclear cells (PBMCs). Specifically, it inhibits the lipopolysaccharide-stimulated release of TNF-alpha at a concentration of 100 µM, achieving a reduction of 15.0%. An assay using enzyme-linked immunosorbent assay (ELISA) indicated that C5 Lenalidomide has an IC50 value greater than 100,000.0 nM for reducing LPS-induced TNF-alpha production in these cells. Additionally, it displaces fluorescent tracers from NanoLuc-tagged CRBN in a NanoBRET assay with an IC50 of 382.0 nM. In human MOLT-4 cells, C5 Lenalidomide demonstrates Protac activity by inducing the degradation of IKZF1 with a maximum reduction of 15.0% after 24 hours and a DC50 greater than 10.0 µM for this degradation..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

C5 Lenalidomide is an chemical weith inconclusive biological activity.

Chemical Properties

Molecular Weight	259.26
Formula	C₁₃H₁₃N₃O₃
Cas No.	191732-70-4
Smiles	O=C1N(CC=2C1=CC=C(N)C2)C3C(=O)NC(=O)CC3
Relative Density.	1.460 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (192.86 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8571 mL	19.2857 mL	38.5713 mL	192.8566 mL
5 mM	0.7714 mL	3.8571 mL	7.7143 mL	38.5713 mL
10 mM	0.3857 mL	1.9286 mL	3.8571 mL	19.2857 mL
20 mM	0.1929 mL	0.9643 mL	1.9286 mL	9.6428 mL
50 mM	0.0771 mL	0.3857 mL	0.7714 mL	3.8571 mL
100 mM	0.0386 mL	0.1929 mL	0.3857 mL	1.9286 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc