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Zeleciment

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Catalog No. T9901A-106Cas No. 2725863-34-1
Alias DYNE-251 Antibody

Zeleciment (DYNE-251 Antibody) is a humanized monoclonal antibody targeting TFRC (CD71). This product binds specifically to transferrin receptor 1 (TfR1) and facilitates the targeted delivery of conjugated nucleotide payloads (such as ASOs or PMOs) to muscle tissues via receptor-mediated endocytosis. It is a vital tool for researching the treatment of muscle diseases, including Duchenne muscular dystrophy (DMD) and myotonic dystrophy (DM1).

Zeleciment

Zeleciment

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Catalog No. T9901A-106Alias DYNE-251 AntibodyCas No. 2725863-34-1
Zeleciment (DYNE-251 Antibody) is a humanized monoclonal antibody targeting TFRC (CD71). This product binds specifically to transferrin receptor 1 (TfR1) and facilitates the targeted delivery of conjugated nucleotide payloads (such as ASOs or PMOs) to muscle tissues via receptor-mediated endocytosis. It is a vital tool for researching the treatment of muscle diseases, including Duchenne muscular dystrophy (DMD) and myotonic dystrophy (DM1).
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Zeleciment (DYNE-251 Antibody) is a humanized monoclonal antibody targeting TFRC (CD71). This product binds specifically to transferrin receptor 1 (TfR1) and facilitates the targeted delivery of conjugated nucleotide payloads (such as ASOs or PMOs) to muscle tissues via receptor-mediated endocytosis. It is a vital tool for researching the treatment of muscle diseases, including Duchenne muscular dystrophy (DMD) and myotonic dystrophy (DM1).
SynonymsDYNE-251 Antibody
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetTransferrin receptor/CD71
Chemical Properties
Cas No.2725863-34-1
Antibody Information
IsotypeIgG1-Fab
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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