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Zeleciment (DYNE-251 Antibody) is a humanized monoclonal antibody targeting TFRC (CD71). This product binds specifically to transferrin receptor 1 (TfR1) and facilitates the targeted delivery of conjugated nucleotide payloads (such as ASOs or PMOs) to muscle tissues via receptor-mediated endocytosis. It is a vital tool for researching the treatment of muscle diseases, including Duchenne muscular dystrophy (DMD) and myotonic dystrophy (DM1).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry | |
| 10 mg | Inquiry | Inquiry | Inquiry |
| Description | Zeleciment (DYNE-251 Antibody) is a humanized monoclonal antibody targeting TFRC (CD71). This product binds specifically to transferrin receptor 1 (TfR1) and facilitates the targeted delivery of conjugated nucleotide payloads (such as ASOs or PMOs) to muscle tissues via receptor-mediated endocytosis. It is a vital tool for researching the treatment of muscle diseases, including Duchenne muscular dystrophy (DMD) and myotonic dystrophy (DM1). |
| Synonyms | DYNE-251 Antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | Transferrin receptor/CD71 |
| Cas No. | 2725863-34-1 |
| Isotype | IgG1-Fab |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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