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Anti-HER2/ERBB2 Antibody (8K444)
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Catalog No. TMAC-01805
Alias TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340
Anti-HER2/ERBB2 Antibody (8K444) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (8K444) can be used in IHC,IF,WB.
Anti-HER2/ERBB2 Antibody (8K444)
Anti-HER2/ERBB2 Antibody (8K444)
😃Good
Catalog No. TMAC-01805Alias TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340
Anti-HER2/ERBB2 Antibody (8K444) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (8K444) can be used in IHC,IF,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-HER2/ERBB2 Antibody (8K444) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (8K444) can be used in IHC,IF,WB. |
| Synonyms | TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340 |
| Ig Type | IgG2a, Kappa |
| Reactivity | Human |
| Verified Activity | 1. Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Her-2(ABT088) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: MCF7, Predicted band size: 137kDa, Observed band size: 200kDa. 2. Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Her-2(ABT088) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: SK-BR-3, Predicted band size: 137kDa, Observed band size: 200kDa. 3. Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Her-2(ABT008) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: T47D, Predicted band size: 137kDa, Observed band size: 180kDa. 4. Human breast carcinoma tissue was stained with Anti-Her-2 (ABT008) Antibody. 5. Human breast carcinoma tissue was stained with Anti-Her-2 (ABT008) Antibody. 6. Human metastatic hepatocellular carcinoma of the breast tissue was stained with Anti-Her-2 (ABT008) Antibody. |
| Application | |
| Recommended Dose | IHC: 1:100-500 IF: 1:100-500 WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: human Her-2 |
| Antigen Species | human |
| Gene ID | |
| Uniprot ID |
| Molecular Weight | Theoretical: 137 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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