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Anti-HGF/SF Antibody (TAK-701)
(Synonyms: TAK-701) Copy Product Info
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Synonyms: TAK-701
Catalog No. T9901A-1423 Copy Product Info
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Anti-HGF/SF Antibody (TAK-701) represents a highly specialized humanized monoclonal antibody specifically engineered to target the human hepatocyte growth factor which acts as a pivotal ligand for the c-Met receptor tyrosine kinase across various malignancies, effectively facilitating the measurable neutralization of HGF-induced signaling to evaluate its role in cancer cell survival and metastasis during strictly monitored laboratory observation periods.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-HGF/SF Antibody (TAK-701) represents a highly specialized humanized monoclonal antibody specifically engineered to target the human hepatocyte growth factor which acts as a pivotal ligand for the c-Met receptor tyrosine kinase across various malignancies, effectively facilitating the measurable neutralization of HGF-induced signaling to evaluate its role in cancer cell survival and metastasis during strictly monitored laboratory observation periods. |
| In vitro | In co-culture assays using NSCLC cell lines and HGF-secreting fibroblasts, Anti-HGF/SF Antibody (TAK-701) blocked HGF-induced c-MET phosphorylation and reversed gefitinib resistance [1]. |
| In vivo | In mouse models of NSCLC with tumor-derived HGF, systemic administration of Anti-HGF/SF Antibody (TAK-701) suppressed tumor growth and enhanced the efficacy of EGFR inhibitors [1]. |
| Synonyms | TAK-701 |
| Clone | TAK-701 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | HGF/SF |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-HGF/SF Antibody (TAK-701) chemical structure | Anti-HGF/SF Antibody (TAK-701) in vivo | Anti-HGF/SF Antibody (TAK-701) in vitro
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