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urolithin M6 (Synonyms: 3,8,9,10-tetrahydroxy urolithin)

Name: urolithin M6
Brand: TargetMol
SKU: T8878
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T8878 Copy Product Info

Purity: 99.63%

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urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic

urolithin M6

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Catalog No. T8878

Synonyms 3,8,9,10-tetrahydroxy urolithin

urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic

Cas No. 1006683-97-1

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Pack Size	Price	USA Stock	Global Stock
1 mg	$195	In Stock	In Stock
5 mg	$483	In Stock	In Stock
10 mg	$692	In Stock	In Stock
25 mg	$1,080	In Stock	In Stock
50 mg	$1,490	-	In Stock
100 mg	$1,970	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.63%

Appearance:Solid

Color:White to Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic
In vitro	UM6 was investigated for its effect on lactic acid production and cell proliferation on Raji cell line. It exerted an evident effect on lactate production (IC50 = 36 ± 3 μM) and inhibited the cell growth with an IC50 of 25 ± 2 μM[1].
Synonyms	3,8,9,10-tetrahydroxy urolithin

Chemical Properties

Molecular Weight	260.2
Formula	C₁₃H₈O₆
Cas No.	1006683-97-1
Smiles	OC1=C2C=3C(OC(=O)C2=CC(O)=C1O)=CC(O)=CC3
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (249.81 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8432 mL	19.2160 mL	38.4320 mL	192.1599 mL
5 mM	0.7686 mL	3.8432 mL	7.6864 mL	38.4320 mL
10 mM	0.3843 mL	1.9216 mL	3.8432 mL	19.2160 mL
20 mM	0.1922 mL	0.9608 mL	1.9216 mL	9.6080 mL
50 mM	0.0769 mL	0.3843 mL	0.7686 mL	3.8432 mL
100 mM	0.0384 mL	0.1922 mL	0.3843 mL	1.9216 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc