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urolithin M6

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Catalog No. T8878Cas No. 1006683-97-1
Alias 3,8,9,10-tetrahydroxy urolithin

urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic

urolithin M6

urolithin M6

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Purity: 99.63%
Catalog No. T8878Alias 3,8,9,10-tetrahydroxy urolithinCas No. 1006683-97-1
urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$195In StockIn Stock
5 mg$483In StockIn Stock
10 mg$692In StockIn Stock
25 mg$1,080In StockIn Stock
50 mg$1,490-In Stock
100 mg$1,970-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.63%
Appearance:Solid
Color:White to Yellow
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Product Introduction

Bioactivity
Description
urolithin M6 (3,8,9,10-tetrahydroxy urolithin) (UM6) is an ellagitannin metabolite produced by gut microbiota, was identified as a putative galloflavin mimetic
In vitro
UM6 was investigated for its effect on lactic acid production and cell proliferation on Raji cell line. It exerted an evident effect on lactate production (IC50 = 36 ± 3 μM) and inhibited the cell growth with an IC50 of 25 ± 2 μM[1].
Synonyms3,8,9,10-tetrahydroxy urolithin
Chemical Properties
Molecular Weight260.2
FormulaC13H8O6
Cas No.1006683-97-1
SmilesOC1=C2C=3C(OC(=O)C2=CC(O)=C1O)=CC(O)=CC3
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 65 mg/mL (249.81 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.8432 mL19.2160 mL38.4320 mL192.1599 mL
5 mM0.7686 mL3.8432 mL7.6864 mL38.4320 mL
10 mM0.3843 mL1.9216 mL3.8432 mL19.2160 mL
20 mM0.1922 mL0.9608 mL1.9216 mL9.6080 mL
50 mM0.0769 mL0.3843 mL0.7686 mL3.8432 mL
100 mM0.0384 mL0.1922 mL0.3843 mL1.9216 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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