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Terodiline

🥰Excellent
TargetMol
Catalog No. T60536Cas No. 15793-40-5

Terodiline is a seconal amine with anticholinergic and calcium antagonistic properties that blocks the hERG current (IC50: 375 nM).Terodiline is cardiotoxic and has been used in the study of disorders caused by urethral muscle instability.

Terodiline
Other Forms of Terodiline:
Terodiline hydrochlorideT131297082-21-5
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Terodiline

🥰Excellent
TargetMol
Purity: 99.59%
Catalog No. T60536Cas No. 15793-40-5
Terodiline is a seconal amine with anticholinergic and calcium antagonistic properties that blocks the hERG current (IC50: 375 nM).Terodiline is cardiotoxic and has been used in the study of disorders caused by urethral muscle instability.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$293In StockIn Stock
5 mg$722In StockIn Stock
10 mg$987In StockIn Stock
25 mg$1,520In StockIn Stock
50 mg$1,980In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.59%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Terodiline is a seconal amine with anticholinergic and calcium antagonistic properties that blocks the hERG current (IC50: 375 nM).Terodiline is cardiotoxic and has been used in the study of disorders caused by urethral muscle instability.
In vivo
In Hartley guinea pigs weighing 200-600 g (female or male), Terodiline (80 mg/kg; administered subcutaneously) yielded an ID50 of 24±6 mg/kg. Higher doses were lethal[1].
Chemical Properties
Molecular Weight281.44
FormulaC20H27N
Cas No.15793-40-5
SmilesC=1C=CC(=CC1)C(C=2C=CC=CC2)CC(NC(C)(C)C)C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 100 mg/mL (355.3 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5532 mL17.7658 mL35.5316 mL177.6578 mL
5 mM0.7106 mL3.5532 mL7.1063 mL35.5316 mL
10 mM0.3553 mL1.7766 mL3.5532 mL17.7658 mL
20 mM0.1777 mL0.8883 mL1.7766 mL8.8829 mL
50 mM0.0711 mL0.3553 mL0.7106 mL3.5532 mL
100 mM0.0355 mL0.1777 mL0.3553 mL1.7766 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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Keywords

hERGCholinergicCalciumChannelCalcium ChannelCa(2+) receptor
Related Tags: buy Terodiline | purchase Terodiline | Terodiline cost | order Terodiline | Terodiline chemical structure | Terodiline in vivo | Terodiline formula | Terodiline molecular weight
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