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DB722

Name: DB722
Brand: TargetMol
SKU: T64372
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T64372Cas No. 433735-90-1

DB722 is a furamidine analogues with DNA binding activity. DB722 shows antiproliferative activity.

DB722

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Purity: 99.91%

Catalog No. T64372Cas No. 433735-90-1

DB722 is a furamidine analogues with DNA binding activity. DB722 shows antiproliferative activity.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
5 mg	$447	In Stock	In Stock
10 mg	$659	In Stock	In Stock
25 mg	$987	In Stock	In Stock
50 mg	$1,380	In Stock	In Stock
100 mg	$1,890	In Stock	In Stock
500 mg	$3,790	-	In Stock
1 mL x 10 mM (in DMSO)	$442	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.91%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	DB722 is a furamidine analogues with DNA binding activity. DB722 shows antiproliferative activity.
In vitro	DB722 inhibits B16 cell growth with IC50 of 8.6μM[1].

Chemical Properties

Molecular Weight	328.37
Formula	C₂₀H₁₆N₄O
Cas No.	433735-90-1
Smiles	C=1(NC=2C(N1)=CC=CC2)C=3OC(=CC3)C4=CC=C(C=C4)C=5NCCN5
Relative Density.	1.38 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (167.49 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0453 mL	15.2267 mL	30.4535 mL	152.2673 mL
5 mM	0.6091 mL	3.0453 mL	6.0907 mL	30.4535 mL
10 mM	0.3045 mL	1.5227 mL	3.0453 mL	15.2267 mL
20 mM	0.1523 mL	0.7613 mL	1.5227 mL	7.6134 mL
50 mM	0.0609 mL	0.3045 mL	0.6091 mL	3.0453 mL
100 mM	0.0305 mL	0.1523 mL	0.3045 mL	1.5227 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc