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ICG-OSu

Name: ICG-OSu
Brand: TargetMol
SKU: T39096
Rating: 4.5 (1 reviews)

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Catalog No. T39096Cas No. 1622335-40-3

Alias ICG NHS ester

ICG-OSu, also known as ICG NHS ester, is a near-infrared fluorescent dye with amine-reactive functionality that enables efficient covalent conjugation to biomolecules, ICG-OSu is widely utilized for the development of in vivo imaging probes, supporting applications in optical imaging, biodistribution studies, and real-time visualization of biological processes.

ICG-OSu

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Catalog No. T39096Alias ICG NHS esterCas No. 1622335-40-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$681	2-4 weeks	2-4 weeks
25 mg	$1,390	2-4 weeks	2-4 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	ICG-OSu, also known as ICG NHS ester, is a near-infrared fluorescent dye with amine-reactive functionality that enables efficient covalent conjugation to biomolecules, ICG-OSu is widely utilized for the development of in vivo imaging probes, supporting applications in optical imaging, biodistribution studies, and real-time visualization of biological processes.
In vitro	ICG-OSu functions as an amine-reactive NIR fluorescent probe that specifically targets primary amines (-NH2) on proteins and antibodies [1].
Synonyms	ICG NHS ester

Chemical Properties

Molecular Weight	828.04
Formula	C₄₉H₅₃N₃O₇S
Cas No.	1622335-40-3
Smiles	O=C(ON1C(=O)CCC1=O)CCCCC[N+]=2C=3C=CC=4C=CC=CC4C3C(C2C=CC=CC=CC=C5N(C=6C=CC=7C=CC=CC7C6C5(C)C)CCCCS(=O)(=O)[O-])(C)C

Storage & Solubility Information

Storage

keep away from direct sunlight | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (48.31 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2077 mL	6.0384 mL	12.0767 mL	60.3836 mL
5 mM	0.2415 mL	1.2077 mL	2.4153 mL	12.0767 mL
10 mM	0.1208 mL	0.6038 mL	1.2077 mL	6.0384 mL
20 mM	0.0604 mL	0.3019 mL	0.6038 mL	3.0192 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ICG-OSuICGOSuICG OSu