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Neutrophil Gelatinase Associated Lipocalin (NGAL), Human

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Catalog No. TRP-00572

Neutrophil Gelatinase Associated Lipocalin (NGAL), Human (EC 6.1.1.3), is part of the lipid transport protein family and is primarily secreted by activated neutrophils. It binds to MMP-9, enhancing its activity and preventing its degradation. NGAL is mainly recognized as a biomarker for acute kidney injury and is released following renal tubular damage and during kidney regeneration.

Neutrophil Gelatinase Associated Lipocalin (NGAL), Human

Neutrophil Gelatinase Associated Lipocalin (NGAL), Human

😃Good
Catalog No. TRP-00572
Neutrophil Gelatinase Associated Lipocalin (NGAL), Human (EC 6.1.1.3), is part of the lipid transport protein family and is primarily secreted by activated neutrophils. It binds to MMP-9, enhancing its activity and preventing its degradation. NGAL is mainly recognized as a biomarker for acute kidney injury and is released following renal tubular damage and during kidney regeneration.
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Description
Neutrophil Gelatinase Associated Lipocalin (NGAL), Human (EC 6.1.1.3), is part of the lipid transport protein family and is primarily secreted by activated neutrophils. It binds to MMP-9, enhancing its activity and preventing its degradation. NGAL is mainly recognized as a biomarker for acute kidney injury and is released following renal tubular damage and during kidney regeneration.
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Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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