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18-Methoxycoronaridine is a nicotinic α3β4 antagonist. 18-Methoxycoronaridine slows the rate of induction of behavioral sensitization to nicotine. 18-MC inhibits α3β4 nicotinic acetylcholine receptors which are densely expressed in the medial habenula and interpeduncular nucleus. 18-Methoxycoronaridine also attenuates sucrose reward, decrease sucrose intake and prevent the development of sucrose-induced obesity.
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Description | 18-Methoxycoronaridine is a nicotinic α3β4 antagonist. 18-Methoxycoronaridine slows the rate of induction of behavioral sensitization to nicotine. 18-MC inhibits α3β4 nicotinic acetylcholine receptors which are densely expressed in the medial habenula and |
Alias | 18Methoxycoronaridine, 18-MC, 18MC, 18 MC |
Molecular Weight | 368.477 |
Formula | C22H28N2O3 |
Cas No. | 308123-60-6 |
Relative Density. | 1.257g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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