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Trityl candesartan

Catalog No. T65740 Copy Product Info
Purity: 99.33%
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Trityl candesartan is a crucial intermediate used in the synthesis of Candesartan and Candesartan cilexetil, which are angiotensin II receptor antagonists.

Trityl candesartan

Copy Product Info
🥰Excellent
Catalog No. T65740

Trityl candesartan is a crucial intermediate used in the synthesis of Candesartan and Candesartan cilexetil, which are angiotensin II receptor antagonists.

Trityl candesartan
Cas No. 139481-72-4
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Pack SizePriceUSA StockGlobal StockQuantity
100 mg$39-In Stock
500 mg$96-In Stock
1 g$138-In Stock
2 g$198-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:99.33%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Trityl candesartan is a crucial intermediate used in the synthesis of Candesartan and Candesartan cilexetil, which are angiotensin II receptor antagonists.
In vitro
Trityl candesartan behaves as a peroxyl radical scavenger. Furthermore, this higher antioxidant activity works in parallel with the improvement of the expansive activity over the angiotensin II-induced contracted human mesangial cells.[1]
Chemical Properties
Molecular Weight682.77
FormulaC43H34N6O3
Cas No.139481-72-4
SmilesCCOC1=NC2=CC=CC(C(O)=O)=C2N1CC1=CC=C(C=C1)C1=C(C=CC=C1)C1=NN=NN1C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (73.23 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4646 mL7.3231 mL14.6462 mL73.2311 mL
5 mM0.2929 mL1.4646 mL2.9292 mL14.6462 mL
10 mM0.1465 mL0.7323 mL1.4646 mL7.3231 mL
20 mM0.0732 mL0.3662 mL0.7323 mL3.6616 mL
50 mM0.0293 mL0.1465 mL0.2929 mL1.4646 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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