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Radretumab
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Catalog No. T9901A-1305 Copy Product Info
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Radretumab (also known as L19SIP) is a fully human monoclonal antibody in a small immunoprotein (SIP) format that specifically targets the extra-domain B (ED-B) of fibronectin. ED-B is a crucial marker of angiogenesis, highly expressed in the extracellular matrix of neovasculature within various solid tumors but nearly absent in normal adult tissues. Radretumab is typically labeled with radioisotopes such as 131I to deliver ionizing radiation directly to tumor sites through high-affinity binding to tumor vessels. In clinical trials, it is investigated for treating solid tumors and associated brain metastases.
Cas No. 1253180-81-2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $447 | - | In Stock | |
| 5 mg | $1,400 | - | In Stock | |
| 25 mg | $4,210 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.5% (SDS-PAGE); 99.0% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Radretumab (also known as L19SIP) is a fully human monoclonal antibody in a small immunoprotein (SIP) format that specifically targets the extra-domain B (ED-B) of fibronectin. ED-B is a crucial marker of angiogenesis, highly expressed in the extracellular matrix of neovasculature within various solid tumors but nearly absent in normal adult tissues. Radretumab is typically labeled with radioisotopes such as 131I to deliver ionizing radiation directly to tumor sites through high-affinity binding to tumor vessels. In clinical trials, it is investigated for treating solid tumors and associated brain metastases. |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | Fibronectin |
| Cas No. | 1253180-81-2 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Radretumab chemical structure
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