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5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione

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Catalog No. TN7149Cas No. 5453-51-0
Alias (5Z)-5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione, (4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol

5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione ((4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol) is a marine derived natural products found in Leptopsammia pruvoti.

5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione

5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione

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Purity: 99.97%
Catalog No. TN7149Alias (5Z)-5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione, (4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diolCas No. 5453-51-0
5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione ((4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol) is a marine derived natural products found in Leptopsammia pruvoti.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$195-In Stock
2 mg$293-In Stock
5 mg$449-In Stock
10 mg$659-In Stock
25 mg$987-In Stock
50 mg$1,390-In Stock
1 mL x 10 mM (in DMSO)$383-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.97%
Appearance:Solid
Color:Yellow
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Product Introduction

Bioactivity
Description
5-[(1H-indol-3-yl)methylidene]imidazolidine-2,4-dione ((4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol) is a marine derived natural products found in Leptopsammia pruvoti.
Synonyms(5Z)-5-(1H-indol-3-ylmethylidene)imidazolidine-2,4-dione, (4Z)-4-(1H-indol-3-ylmethylidene)-4H-imidazole-2,5-diol
Chemical Properties
Molecular Weight227.22
FormulaC12H9N3O2
Cas No.5453-51-0
SmilesO=C1NC(=O)\C(N1)=C/C1=CNC2=C1C=CC=C2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (242.06 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4010 mL22.0051 mL44.0102 mL220.0511 mL
5 mM0.8802 mL4.4010 mL8.8020 mL44.0102 mL
10 mM0.4401 mL2.2005 mL4.4010 mL22.0051 mL
20 mM0.2201 mL1.1003 mL2.2005 mL11.0026 mL
50 mM0.0880 mL0.4401 mL0.8802 mL4.4010 mL
100 mM0.0440 mL0.2201 mL0.4401 mL2.2005 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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