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Mal-Deferoxamine

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Catalog No. T210527Cas No. 1638156-31-6

Mal-Deferoxamine is a maleimide-functionalized derivative of Deferoxamine in which the maleamide group enables highly selective and covalent conjugation with thiol-containing biomolecules, forming stable linkages suited for chemical biology and radiopharmaceutical engineering. Mal-Deferoxamine readily chelates medical radionuclides to generate radionuclide drug conjugates (RDCs), which permit targeted molecular imaging or therapeutic delivery owing to their ability to engage specific biomolecular targets with high affinity, making this compound a versatile scaffold for the development of diagnostic probes and radiotheranostic agents.

Mal-Deferoxamine

Mal-Deferoxamine

😃Good
Purity: 95%
Catalog No. T210527Cas No. 1638156-31-6
Mal-Deferoxamine is a maleimide-functionalized derivative of Deferoxamine in which the maleamide group enables highly selective and covalent conjugation with thiol-containing biomolecules, forming stable linkages suited for chemical biology and radiopharmaceutical engineering. Mal-Deferoxamine readily chelates medical radionuclides to generate radionuclide drug conjugates (RDCs), which permit targeted molecular imaging or therapeutic delivery owing to their ability to engage specific biomolecular targets with high affinity, making this compound a versatile scaffold for the development of diagnostic probes and radiotheranostic agents.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50-In Stock
5 mg$110-In Stock
10 mg$166-In Stock
25 mg$282-In Stock
50 mg$456-In Stock
1 mL x 10 mM (in DMSO)$310-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:95%
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Product Introduction

Bioactivity
Description
Mal-Deferoxamine is a maleimide-functionalized derivative of Deferoxamine in which the maleamide group enables highly selective and covalent conjugation with thiol-containing biomolecules, forming stable linkages suited for chemical biology and radiopharmaceutical engineering. Mal-Deferoxamine readily chelates medical radionuclides to generate radionuclide drug conjugates (RDCs), which permit targeted molecular imaging or therapeutic delivery owing to their ability to engage specific biomolecular targets with high affinity, making this compound a versatile scaffold for the development of diagnostic probes and radiotheranostic agents.
Chemical Properties
Molecular Weight711.8
FormulaC32H53N7O11
Cas No.1638156-31-6
SmilesO=C1C=CC(=O)N1CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)C
Relative Density.no data available
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 65.00 mg/mL (91.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4049 mL7.0244 mL14.0489 mL70.2445 mL
5 mM0.2810 mL1.4049 mL2.8098 mL14.0489 mL
10 mM0.1405 mL0.7024 mL1.4049 mL7.0244 mL
20 mM0.0702 mL0.3512 mL0.7024 mL3.5122 mL
50 mM0.0281 mL0.1405 mL0.2810 mL1.4049 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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