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Mal-Deferoxamine

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Catalog No. T210527Cas No. 1638156-31-6

Mal-Deferoxamine is a maleimide-functionalized derivative of Deferoxamine in which the maleamide group enables highly selective and covalent conjugation with thiol-containing biomolecules, forming stable linkages suited for chemical biology and radiopharmaceutical engineering. Mal-Deferoxamine readily chelates medical radionuclides to generate radionuclide drug conjugates (RDCs), which permit targeted molecular imaging or therapeutic delivery owing to their ability to engage specific biomolecular targets with high affinity, making this compound a versatile scaffold for the development of diagnostic probes and radiotheranostic agents.

Mal-Deferoxamine

Mal-Deferoxamine

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Purity: 95%
Catalog No. T210527Cas No. 1638156-31-6
Mal-Deferoxamine is a maleimide-functionalized derivative of Deferoxamine in which the maleamide group enables highly selective and covalent conjugation with thiol-containing biomolecules, forming stable linkages suited for chemical biology and radiopharmaceutical engineering. Mal-Deferoxamine readily chelates medical radionuclides to generate radionuclide drug conjugates (RDCs), which permit targeted molecular imaging or therapeutic delivery owing to their ability to engage specific biomolecular targets with high affinity, making this compound a versatile scaffold for the development of diagnostic probes and radiotheranostic agents.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50-In Stock
5 mg$110-In Stock
10 mg$166-In Stock
25 mg$282-In Stock
50 mg$456-In Stock
1 mL x 10 mM (in DMSO)$310-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:95%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Mal-Deferoxamine is a maleimide-functionalized derivative of Deferoxamine in which the maleamide group enables highly selective and covalent conjugation with thiol-containing biomolecules, forming stable linkages suited for chemical biology and radiopharmaceutical engineering. Mal-Deferoxamine readily chelates medical radionuclides to generate radionuclide drug conjugates (RDCs), which permit targeted molecular imaging or therapeutic delivery owing to their ability to engage specific biomolecular targets with high affinity, making this compound a versatile scaffold for the development of diagnostic probes and radiotheranostic agents.
Chemical Properties
Molecular Weight711.8
FormulaC32H53N7O11
Cas No.1638156-31-6
SmilesO=C1C=CC(=O)N1CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)CCC(=O)NCCCCCN(O)C(=O)C
Relative Density.no data available
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 65.00 mg/mL (91.32 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4049 mL7.0244 mL14.0489 mL70.2445 mL
5 mM0.2810 mL1.4049 mL2.8098 mL14.0489 mL
10 mM0.1405 mL0.7024 mL1.4049 mL7.0244 mL
20 mM0.0702 mL0.3512 mL0.7024 mL3.5122 mL
50 mM0.0281 mL0.1405 mL0.2810 mL1.4049 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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