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(S)-VU0637120

Name: (S)-VU0637120
Brand: TargetMol
SKU: T71321
Price: 176 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T71321Cas No. 1175940-86-9

(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.

(S)-VU0637120

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Purity: 99.74%

Catalog No. T71321Cas No. 1175940-86-9

(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.

Pack Size	Price	Availability
1 mg	$176	In Stock
5 mg	$433	In Stock
10 mg	$615	In Stock
25 mg	$912	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.74%

ee:100%

Resource Download

COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description	(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.
Targets&IC50	Neuropeptide Y (NPY) Y4 receptor:2.8 μM, Neuropeptide Y (NPY) Y4 receptor:300-400 nM (Kb)

Chemical Properties

Molecular Weight	397.47
Formula	C₁₆H₁₉N₃O₅S₂
Cas No.	1175940-86-9
Smiles	N(C(=O)[C@H]1N(S(C)(=O)=O)CCCC1)C2=NC=3C(=CC4=C(C3)OCCO4)S2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (125.8 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5159 mL	12.5796 mL	25.1591 mL	125.7957 mL
5 mM	0.5032 mL	2.5159 mL	5.0318 mL	25.1591 mL
10 mM	0.2516 mL	1.2580 mL	2.5159 mL	12.5796 mL
20 mM	0.1258 mL	0.6290 mL	1.2580 mL	6.2898 mL
50 mM	0.0503 mL	0.2516 mL	0.5032 mL	2.5159 mL
100 mM	0.0252 mL	0.1258 mL	0.2516 mL	1.2580 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc