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(S)-VU0637120

Name: (S)-VU0637120
Brand: TargetMol
SKU: T71321
Price: 176 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T71321Cas No. 1175940-86-9

(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.

(S)-VU0637120

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Purity: 99.74%

Catalog No. T71321Cas No. 1175940-86-9

(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$176	In Stock	In Stock
5 mg	$433	In Stock	In Stock
10 mg	$615	In Stock	In Stock
25 mg	$912	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.74%

ee:100%

Appearance:Solid

Color:White

Resource Download

COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description	(S)-VU0637120 is a selective neuropeptide Y(4)R-mutant antagonist used in the study of metabolic disorders.
Targets&IC50	Neuropeptide Y (NPY) Y4 receptor:300-400 nM (Kb), Neuropeptide Y (NPY) Y4 receptor:2.8 μM

Chemical Properties

Molecular Weight	397.47
Formula	C₁₆H₁₉N₃O₅S₂
Cas No.	1175940-86-9
Smiles	N(C(=O)[C@H]1N(S(C)(=O)=O)CCCC1)C2=NC=3C(=CC4=C(C3)OCCO4)S2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (125.8 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5159 mL	12.5796 mL	25.1591 mL	125.7957 mL
5 mM	0.5032 mL	2.5159 mL	5.0318 mL	25.1591 mL
10 mM	0.2516 mL	1.2580 mL	2.5159 mL	12.5796 mL
20 mM	0.1258 mL	0.6290 mL	1.2580 mL	6.2898 mL
50 mM	0.0503 mL	0.2516 mL	0.5032 mL	2.5159 mL
100 mM	0.0252 mL	0.1258 mL	0.2516 mL	1.2580 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc