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Anti-Cadherin 8/CDH8 Antibody (2O370)
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Catalog No. TMAY-00340
Alias cadherin 8, type 2
Anti-Cadherin 8/CDH8 Antibody (2O370) is a Rabbit antibody targeting Cadherin 8/CDH8. Anti-Cadherin 8/CDH8 Antibody (2O370) can be used in ELISA.
Anti-Cadherin 8/CDH8 Antibody (2O370)
Anti-Cadherin 8/CDH8 Antibody (2O370)
😃Good
Catalog No. TMAY-00340Alias cadherin 8, type 2
Anti-Cadherin 8/CDH8 Antibody (2O370) is a Rabbit antibody targeting Cadherin 8/CDH8. Anti-Cadherin 8/CDH8 Antibody (2O370) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $270 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-Cadherin 8/CDH8 Antibody (2O370) is a Rabbit antibody targeting Cadherin 8/CDH8. Anti-Cadherin 8/CDH8 Antibody (2O370) can be used in ELISA. |
| Alias | cadherin 8, type 2 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2O370 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Cadherin-8 / CDH8 (rh Cadherin-8 / CDH8; TMPY-01038; NP_001787.2; Met1-Met621). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cadherins are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Type I cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of five subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherin 8, also known as CDH 8, is a type II classical cadherin belonging to the cadherin superfamily. As mainly expressed in brain, CDH8 is found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts, and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Human Cadherin 8 is a 799 amino acid single-pass type Itransmembrane protein with a putative 29 aa signal sequence, and a 32 aa propeptide, a 56 aa mature extracellular domain, a 21 aa transmembrane domain and a 157 aa cytoplasmic domain. The human, mouse and rat proteins share approximately 98% homology. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Cadherin-8 / CDH8 Protein (TMPY-01038) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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