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Tenatumomab
(Synonyms: ST-2146, ST2146, ST 2146) Copy Product Info
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Synonyms: ST-2146, ST2146, ST 2146
Catalog No. T78308 Copy Product Info
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Tenatumomab (ST2146) is a mouse-derived monoclonal antibody that specifically recognizes and targets human Tenascin-C (TNC). Tenatumomab is commonly used in the study of solid tumors and hematologic malignancies. Tenatumomab is widely used in experiments such as immunohistochemistry (IHC) to detect the expression and distribution of Tenascin-C in tumor tissues. It can also serve as a radiopharmaceutical delivery vector; when radiolabeled (e.g., 131I-Tenatumomab), it is used in research on radioimmunotherapy for Tenascin-C-positive tumors.
Tenatumomab
Cas No. 1412891-40-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $148 | - | In Stock | |
| 5 mg | $368 | - | In Stock | |
| 10 mg | $552 | - | In Stock | |
| 25 mg | $886 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction
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Chemical Properties
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| Description | Tenatumomab (ST2146) is a mouse-derived monoclonal antibody that specifically recognizes and targets human Tenascin-C (TNC). Tenatumomab is commonly used in the study of solid tumors and hematologic malignancies. Tenatumomab is widely used in experiments such as immunohistochemistry (IHC) to detect the expression and distribution of Tenascin-C in tumor tissues. It can also serve as a radiopharmaceutical delivery vector; when radiolabeled (e.g., 131I-Tenatumomab), it is used in research on radioimmunotherapy for Tenascin-C-positive tumors. |
| In vitro | Compared to other tenascin-targeting monoclonal antibodies, Tenatumomab (at 2-5 μg/mL for 16 h) retains 50% of its immunoreactivity after biotinylation [2]. |
| In vivo | Tenatumomab (4 μg per mouse; intravenous injection; single dose) exhibited a biodistribution associated with the expression of low and high tension proteins in nude mice xenografted with human HT-29 colon carcinoma cells and/or human U-118MG glioblastoma cells [2]. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | ST-2146, ST2146, ST 2146 |
| Reactivity | Human |
| Verified Activity | Immobilized Human Tenascin Protein at 2 μg/mL (30μL/well) can bind Tenatumomab (mIgG2b). The EC50 is 0.006586 μg/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Tenascin C |
| Molecular Weight | 147.86 kDa |
| Cas No. | 1412891-40-7 |
| Isotype | Mouse IgG2b kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Tenatumomab in vivo | Tenatumomab in vitro | Tenatumomab molecular weight
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