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K 01-162

Name: K 01-162
Brand: TargetMol
SKU: T13744
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T13744Cas No. 677746-25-7

Alias K162

K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.

K 01-162

😃Good

Catalog No. T13744Alias K162Cas No. 677746-25-7

K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$142	5 days	5 days
25 mg	$916	6-8 weeks	6-8 weeks
50 mg	$1,190	6-8 weeks	6-8 weeks
100 mg	$1,860	6-8 weeks	6-8 weeks
1 mL x 10 mM (in DMSO)	$272	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Product Introduction

Bioactivity

Description	K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.
Synonyms	K162

Chemical Properties

Molecular Weight	288.18
Formula	C₁₅H₁₄BrN
Cas No.	677746-25-7
Smiles	CN(C)c1ccc-2c(Cc3cc(Br)ccc-23)c1
Relative Density.	1.423 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 14.29 mg/mL (49.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4701 mL	17.3503 mL	34.7005 mL	173.5027 mL
5 mM	0.6940 mL	3.4701 mL	6.9401 mL	34.7005 mL
10 mM	0.3470 mL	1.7350 mL	3.4701 mL	17.3503 mL
20 mM	0.1735 mL	0.8675 mL	1.7350 mL	8.6751 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc