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K 01-162

Name: K 01-162
Brand: TargetMol
SKU: T13744
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T13744Cas No. 677746-25-7

Alias K162

K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.

K 01-162

😃Good

Catalog No. T13744Alias K162Cas No. 677746-25-7

K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.

Pack Size	Price	Availability
2 mg	$142	5 days
25 mg	$916	6-8 weeks
50 mg	$1,190	6-8 weeks
100 mg	$1,860	6-8 weeks
1 mL x 10 mM (in DMSO)	$272	5 days

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Product Introduction

Bioactivity

Description	K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.
Synonyms	K162

Chemical Properties

Molecular Weight	288.18
Formula	C₁₅H₁₄BrN
Cas No.	677746-25-7
Relative Density.	1.423 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 14.29 mg/mL (49.59 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4701 mL	17.3503 mL	34.7005 mL	173.5027 mL
5 mM	0.6940 mL	3.4701 mL	6.9401 mL	34.7005 mL
10 mM	0.3470 mL	1.7350 mL	3.4701 mL	17.3503 mL
20 mM	0.1735 mL	0.8675 mL	1.7350 mL	8.6751 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc