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UB-221
Catalog No. T9901A-1750 Copy Product Info
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UB-221 is a humanized IgG1 monoclonal antibody inhibitor that targets IgE. It significantly reduces IgE synthesis by stabilizing the membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated activation and degranulation of basophils. UB-221 lowers IgE levels in cynomolgus monkeys and human IgE (ε, κ) transgenic (hIGHE knock-in) mice, making it relevant for asthma and chronic spontaneous urticaria (CSU) research.
UB-221
Copy Product Info🥰Excellent
Catalog No. T9901A-1750
UB-221 is a humanized IgG1 monoclonal antibody inhibitor that targets IgE. It significantly reduces IgE synthesis by stabilizing the membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated activation and degranulation of basophils. UB-221 lowers IgE levels in cynomolgus monkeys and human IgE (ε, κ) transgenic (hIGHE knock-in) mice, making it relevant for asthma and chronic spontaneous urticaria (CSU) research.
UB-221
Cas No. 2755114-30-6
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | UB-221 is a humanized IgG1 monoclonal antibody inhibitor that targets IgE. It significantly reduces IgE synthesis by stabilizing the membrane-bound CD23 on B lymphocytes and inhibits FcԑRI-mediated activation and degranulation of basophils. UB-221 lowers IgE levels in cynomolgus monkeys and human IgE (ε, κ) transgenic (hIGHE knock-in) mice, making it relevant for asthma and chronic spontaneous urticaria (CSU) research. |
| Cas No. | 2755114-30-6 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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