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Isosorbide-2-nitrate
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Catalog No. T207766Cas No. 16106-20-0
Alias IS 2-MN | Isosorbide 2-mononitrate
Isosorbide-2-nitrate, a nitric oxide (NO) donor and active metabolite of isosorbide dinitrate, inhibits contraction in rabbit aortic strips induced by potassium chloride or angiotensin II and reduces vasopressin-induced coronary spasm in isolated rabbit hearts at concentrations of 100 and 1,000 µM.
Isosorbide-2-nitrate
😃Good
Catalog No. T207766Alias IS 2-MN | Isosorbide 2-mononitrateCas No. 16106-20-0
Isosorbide-2-nitrate, a nitric oxide (NO) donor and active metabolite of isosorbide dinitrate, inhibits contraction in rabbit aortic strips induced by potassium chloride or angiotensin II and reduces vasopressin-induced coronary spasm in isolated rabbit hearts at concentrations of 100 and 1,000 µM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Isosorbide-2-nitrate, a nitric oxide (NO) donor and active metabolite of isosorbide dinitrate, inhibits contraction in rabbit aortic strips induced by potassium chloride or angiotensin II and reduces vasopressin-induced coronary spasm in isolated rabbit hearts at concentrations of 100 and 1,000 µM. |
| Synonyms | IS 2-MN | Isosorbide 2-mononitrate |
| Molecular Weight | 191.14 |
| Formula | C6H9NO6 |
| Cas No. | 16106-20-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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