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5'-Deoxy-5'-methylthioadenosine-d3

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Catalog No. TMID-0168Cas No. 174838-38-1
Alias 5'-S-Methyl-5'-thioadenosine-d3, 5'-Methylthioadenosine-d3, 5'-Deoxy-5'-(methylthio)adenosine-d3, 5'-(Methylthio)-5'-deoxyadenosine-d3

5'-Deoxy-5'-methylthioadenosine-d3 is a stable, deuterium-labeled analogue of the endogenous nucleoside metabolite 5'-Deoxy-5'-methylthioadenosine (MTA, CAS 2457-80-9). this compound retains the tumor cell proliferation inhibitory effects of the parent molecule and is primarily utilized as an internal standard in mass spectrometry-based metabolomic studies to quantify MTA levels in biological samples.

5'-Deoxy-5'-methylthioadenosine-d3

5'-Deoxy-5'-methylthioadenosine-d3

🥰Excellent
Catalog No. TMID-0168Alias 5'-S-Methyl-5'-thioadenosine-d3, 5'-Methylthioadenosine-d3, 5'-Deoxy-5'-(methylthio)adenosine-d3, 5'-(Methylthio)-5'-deoxyadenosine-d3Cas No. 174838-38-1
5'-Deoxy-5'-methylthioadenosine-d3 is a stable, deuterium-labeled analogue of the endogenous nucleoside metabolite 5'-Deoxy-5'-methylthioadenosine (MTA, CAS 2457-80-9). this compound retains the tumor cell proliferation inhibitory effects of the parent molecule and is primarily utilized as an internal standard in mass spectrometry-based metabolomic studies to quantify MTA levels in biological samples.
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Product Introduction

Bioactivity
Description
5'-Deoxy-5'-methylthioadenosine-d3 is a stable, deuterium-labeled analogue of the endogenous nucleoside metabolite 5'-Deoxy-5'-methylthioadenosine (MTA, CAS 2457-80-9). this compound retains the tumor cell proliferation inhibitory effects of the parent molecule and is primarily utilized as an internal standard in mass spectrometry-based metabolomic studies to quantify MTA levels in biological samples.
Synonyms5'-S-Methyl-5'-thioadenosine-d3, 5'-Methylthioadenosine-d3, 5'-Deoxy-5'-(methylthio)adenosine-d3, 5'-(Methylthio)-5'-deoxyadenosine-d3
Chemical Properties
Molecular Weight300.35
FormulaC11H15N5O3S
Cas No.174838-38-1
SmilesNC1=C2N(C=NC2=NC=N1)[C@@H]3O[C@H](CSC([2H])([2H])[2H])[C@@H](O)[C@H]3O
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 0.8 mg/mL (2.66 mM), Sonication is recommended.
DMF: 2 mg/mL (6.66 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMF
1mg5mg10mg50mg
1 mM3.3294 mL16.6472 mL33.2945 mL166.4724 mL
DMF
1mg5mg10mg50mg
5 mM0.6659 mL3.3294 mL6.6589 mL33.2945 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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