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DU717

Name: DU717
Brand: TargetMol
SKU: T11109
Price: 197 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11109Cas No. 59943-31-6

Alias DU-717

DU717 is an antihypertensive agent.

DU717

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🥰Excellent

Purity: 99.64%

Catalog No. T11109Alias DU-717Cas No. 59943-31-6

DU717 is an antihypertensive agent.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$197	In Stock	In Stock
5 mg	$392	In Stock	In Stock
10 mg	$672	In Stock	In Stock
25 mg	$981	In Stock	In Stock
50 mg	$1,350	In Stock	In Stock
100 mg	$1,780	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$427	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.64%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	DU717 is an antihypertensive agent.
In vivo	A gas chromatographic method for the determination of DU717, a novel antihypertensive drug in plasma, was established.The plasma concentration of DU717 ranged from 10-150 ng /mL with a RSD of 6.2%.The minimum detection concentration is 1 ng/mL.Plasma levels of DU717 in spontaneously hypertensive and normal-blood pressure rats were also measured.
Synonyms	DU-717

Chemical Properties

Molecular Weight	314.79
Formula	C₁₂H₁₅ClN₄O₂S
Cas No.	59943-31-6
Smiles	O=S1(=O)C=2C(NC(=N1)N3CCN(C)CC3)=CC=C(Cl)C2
Relative Density.	1.3907 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 150 mg/mL (476.51 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1767 mL	15.8836 mL	31.7672 mL	158.8360 mL
5 mM	0.6353 mL	3.1767 mL	6.3534 mL	31.7672 mL
10 mM	0.3177 mL	1.5884 mL	3.1767 mL	15.8836 mL
20 mM	0.1588 mL	0.7942 mL	1.5884 mL	7.9418 mL
50 mM	0.0635 mL	0.3177 mL	0.6353 mL	3.1767 mL
100 mM	0.0318 mL	0.1588 mL	0.3177 mL	1.5884 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc