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FR179642

(Synonyms: FR-179642, FR 179642) Copy Product Info
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Synonyms: FR-179642, FR 179642

Catalog No. T39148 Copy Product Info
Purity: 99.84%
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FR179642 is a key intermediate in the synthesis of the antifungal drug Micafungin and also corresponds to the cyclic peptide core structure of the lipopeptide natural product FR901379. FR179642 belongs to the structural framework of echinocandin-class antifungal compounds and serves as an important reference in the structural optimization and synthesis of β-1,3-glucan synthase inhibitors.
FR179642
Cas No. 168110-44-9
Pack SizePriceUSA StockGlobal StockQuantity
10 mg$30-In Stock
25 mg$45-In Stock
50 mg$64-In Stock
100 mg$106-In Stock
500 mg$262-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.84%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
FR179642 is a key intermediate in the synthesis of the antifungal drug Micafungin and also corresponds to the cyclic peptide core structure of the lipopeptide natural product FR901379. FR179642 belongs to the structural framework of echinocandin-class antifungal compounds and serves as an important reference in the structural optimization and synthesis of β-1,3-glucan synthase inhibitors.
SynonymsFR-179642, FR 179642
Chemical Properties
Molecular Weight936.90
FormulaC35H52N8O20S
Cas No.168110-44-9
SmilesO=C1N2[C@@]([C@@H](O)[C@@H](C)C2)(C(=O)N[C@H](O)[C@H](O)C[C@H](N)C(=O)N[C@@]([C@@H](C)O)(C(=O)N3[C@](C(=O)N[C@@]([C@@H]([C@@H](O)C4=CC(OS(=O)(=O)O)=C(O)C=C4)O)(C(=O)N[C@]1([C@@H](CC(N)=O)O)[H])[H])(C[C@@H](O)C3)[H])[H])[H]
Storage & Solubility Information
StorageKeep away from moistureKeep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80.00 mg/mL (85.39 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.0673 mL5.3367 mL10.6735 mL53.3675 mL
5 mM0.2135 mL1.0673 mL2.1347 mL10.6735 mL
10 mM0.1067 mL0.5337 mL1.0673 mL5.3367 mL
20 mM0.0534 mL0.2668 mL0.5337 mL2.6684 mL
50 mM0.0213 mL0.1067 mL0.2135 mL1.0673 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Keywords

Related Tags: FR179642 chemical structure | FR179642 formula | FR179642 molecular weight