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BTA-EG4 hydrate
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Catalog No. T72074Cas No. 921193-28-4
BTA-EG4 hydrate can be used to diagnose, prevent or reduce the symptoms of amyloid-related diseases like Alzheimer's disease and can be used to improve cognitive function.
BTA-EG4 hydrate
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Purity: 99.29%
Catalog No. T72074Cas No. 921193-28-4
BTA-EG4 hydrate can be used to diagnose, prevent or reduce the symptoms of amyloid-related diseases like Alzheimer's disease and can be used to improve cognitive function.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $440 | - | In Stock | |
| 10 mg | $660 | - | In Stock | |
| 25 mg | $1,150 | - | In Stock | |
| 50 mg | $1,760 | - | In Stock | |
| 100 mg | $2,720 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.29%
Appearance:Solid
Color:Yellow
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | BTA-EG4 hydrate can be used to diagnose, prevent or reduce the symptoms of amyloid-related diseases like Alzheimer's disease and can be used to improve cognitive function. |
| In vitro | BTA-EG4 (40–60 μM ; 48 h) significantly reduced tau phosphorylation in the absence of any changes in the amounts of amyloid precursor protein, amyloid-β or synaptic proteins.[1] |
| In vivo | BTA-EG4 (30 mg/kg ; injections ; daily ; 2 weeks) improved dendritic spine density and cognitive function of 3xTg AD mice in an age-dependent manner. BTA-EG4 injected 3xTg AD mice at 6-10 months of age showed improved learning and memory ; however, only minimal improvement was observed at 13-16 months of age. This behavioral improvement corresponds to a decrease in soluble Aβ 40 levels. These findings suggest that BTA-EG4 may be beneficial in ameliorating the synaptic loss seen in early AD.[2] |
| Molecular Weight | 416.53 |
| Formula | C22H28N2O4S |
| Cas No. | 921193-28-4 |
| Smiles | OCCOCCOCCOCCNC1=CC=C(C=C1)C2=NC=3C=CC(=CC3S2)C |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 13.5 mg/mL (32.41 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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