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Leucokinin VIII acetate

Name: Leucokinin VIII acetate
Brand: TargetMol
SKU: TP1114L
Price: 87 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TP1114L

Alias Leucokinin 8

Leucokinin VIII acetate (Leucokinin 8) is an diuretic octapeptide isolated form head extracts of the cockroach.

Leucokinin VIII acetate

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Purity: 98.52%

Catalog No. TP1114LAlias Leucokinin 8

Leucokinin VIII acetate (Leucokinin 8) is an diuretic octapeptide isolated form head extracts of the cockroach.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$87	In Stock	In Stock
5 mg	$180	In Stock	In Stock
10 mg	$273	In Stock	In Stock
25 mg	$515	In Stock	In Stock
50 mg	$747	In Stock	In Stock
100 mg	$1,050	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.52%

Appearance:Solid

Color:White

Resource Download

COA MS HPLC

Product Introduction

Bioactivity

Description	Leucokinin VIII acetate (Leucokinin 8) is an diuretic octapeptide isolated form head extracts of the cockroach.
In vitro	Leucokinin VIII is an octapeptide, increases the rates of transepithelial NaC1, KC1 and water secretion, increases the Cl conductance of the epithelial shunt via a receptor located at the basolateral side of the epithelium[1]. Leucokinin VIII also activates Ca2+-dependent signal pathway in principal cells of Aedes aegyptiMalpighian tubules[2].
Synonyms	Leucokinin 8

Chemical Properties

Molecular Weight	932.99
Formula	C₄₄H₅₆N₁₀O₁₃
Smiles	CC(O)=O.O=C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CO)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(NCC(N)=O)=O)=O)=O)=O)=O)=O)CN
Relative Density.	no data available
Sequence	H-Gly-Ala-Ser-Phe-Tyr-Ser-Trp-Gly-NH2
Sequence Short	GASFYSWG

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

Methanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 100 mg/mL (107.18 mM)

H2O: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0718 mL	5.3591 mL	10.7182 mL	53.5911 mL
5 mM	0.2144 mL	1.0718 mL	2.1436 mL	10.7182 mL
10 mM	0.1072 mL	0.5359 mL	1.0718 mL	5.3591 mL
20 mM	0.0536 mL	0.2680 mL	0.5359 mL	2.6796 mL
50 mM	0.0214 mL	0.1072 mL	0.2144 mL	1.0718 mL
100 mM	0.0107 mL	0.0536 mL	0.1072 mL	0.5359 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc