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Adecatumumab
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Catalog No. T77747Cas No. 503605-66-1
Alias MT 201
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.
Adecatumumab
Adecatumumab
😃Good
Catalog No. T77747Alias MT 201Cas No. 503605-66-1
Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $289 | In Stock | In Stock | |
| 5 mg | $788 | In Stock | In Stock | |
| 10 mg | $1,230 | - | In Stock | |
| 25 mg | $1,850 | - | In Stock | |
| 50 mg | $2,490 | - | In Stock | |
| 100 mg | $3,360 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Adecatumumab (MT201) is a whole-person IgG1 monoclonal antibody to human EpCAM. Adecatumumab has potential anticancer activity and can be used to study breast cancer. |
| In vitro | Among human Adecatumumab and murine Adecatumumab, there are diverse kinetic binding activities observed in B16/EpCAM 3E3 cells when treated with Adecatumumab (4 μM; 18 h)[2]. Adecatumumab (0.1 ng/mL-0.1 mg/mL; 4 h) exhibits dose-dependent activity in Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in natural killer (NK) cells[2]. |
| In vivo | In the B16/EpCAM xenograft tumor model in mice, both human adecatumumab and mu-adecatumumab (300 μg/mouse; i.v. bolus injection; 3 times per week) demonstrate inhibition of tumor growth[2]. Both human adecatumumab and mu-adecatumumab (300 μg/mouse; i.v. bolus injection; single dose) display a bi-exponential curve progression of serum concentration, characterized by an early distribution phase between 0 and 10 h and a terminal elimination phase[2]. |
| Synonyms | MT 201 |
| Reactivity | Human |
| Verified Activity | Immobilized Human EpCAM/TROP1/CD326 Protein (His) at 2 μg/mL (30 μL/well) can bind Adecatumumab. The EC50 is 754 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | EpCAM/TROP1/CD326 |
| Molecular Weight | 147.52 kDa |
| Cas No. | 503605-66-1 |
| Relative Density. | no data available |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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