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Anti-Cadherin 6/CDH6 Antibody (5U203)
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Catalog No. TMAY-00362
Alias K-cadherin, KCAD, CDH6, Cadherin-6, Cadherin6, CAD6
Anti-Cadherin 6/CDH6 Antibody (5U203) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (5U203) can be used in ELISA.
Anti-Cadherin 6/CDH6 Antibody (5U203)
Anti-Cadherin 6/CDH6 Antibody (5U203)
😃Good
Catalog No. TMAY-00362Alias K-cadherin, KCAD, CDH6, Cadherin-6, Cadherin6, CAD6
Anti-Cadherin 6/CDH6 Antibody (5U203) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (5U203) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Cadherin 6/CDH6 Antibody (5U203) is a Mouse antibody targeting Cadherin 6/CDH6. Anti-Cadherin 6/CDH6 Antibody (5U203) can be used in ELISA. |
| Alias | K-cadherin, KCAD, CDH6, Cadherin-6, Cadherin6, CAD6 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5U203 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cadherin-6 / K-Cadherin / CDH6 (rh Cadherin-6 / K-Cadherin / CDH6; TMPY-01050; NP_004923.1; Met 1-Ala 615). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progression in a number of adenocarcinomas. Cadherin-6 (CDH6), also known as K-cadherin (KCAD), is a type-II classic cadherin cell-cell adhesion molecules, which are expressed in graded or areal patterns, as well as layer-specific patterns, in the cortical plate. Human Cadherin-6 is synthesized as a 790 aa type I transmembrane glycoprotein that contains an 18 aa signal peptide, a 35 aa propeptide, a 562 aa extracellular region, a 21 aa transmembrane segment, and a 154 aa cytoplasmic domain. There are five cadherin domains of approximately 110 aa each in the extracellular region. Cadherin-6 is highly expressed in brain, cerebellum, and kidney, and may contribute to the formation of the segmental structure of the early brain, as well as the development of renal proximal tubules. Weak expression is also detected lung, pancreas, and gastric mucosa. Additionally, it is specifically expressed in the proximal tubule of normal kidneys and in renal cell cancer. Thus, Cadherin-6 is a new prognostic factor for renal cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human Cadherin-6 / K-Cadherin / CDH6 protein (TMPY-01050) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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