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Nrf2 Activator-6, a tetrahydroisoquinoline compound, functions as an Nrf2 activator, demonstrating potency with an IC50 value of 5 nM in inhibiting the Kelch domain-Nrf2 interaction.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $3,920 | 10-14 weeks | 10-14 weeks | |
| 50 mg | $5,180 | 10-14 weeks | 10-14 weeks | |
| 100 mg | $7,300 | 10-14 weeks | 10-14 weeks |
| Description | Nrf2 Activator-6, a tetrahydroisoquinoline compound, functions as an Nrf2 activator, demonstrating potency with an IC50 value of 5 nM in inhibiting the Kelch domain-Nrf2 interaction. |
| Molecular Weight | 614.11 |
| Formula | C31H37ClFN5O5 |
| Cas No. | 2728780-74-1 |
| Smiles | C([C@@H]1C=2C(CCN1C(=O)[C@H]3[C@](C(O)=O)(C)CCC3)=C(Cl)C=C(F)C2OCC4=C5N(N=N4)CCCC5)N6CC7(CC6=O)CC7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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