Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Antitumor agent-28 is a compound that specifically targets and inhibits the activity of the ataxia telangiectasia mutated (ATM) kinase. By doing so, it effectively impedes the progression of ATM-mediated diseases and demonstrates significant anti-cancer activity.
Pack Size | Availability | Price/USD | Quantity |
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25 mg | Inquiry | $ 1,520.00 |
Description | Antitumor agent-28 is a compound that specifically targets and inhibits the activity of the ataxia telangiectasia mutated (ATM) kinase. By doing so, it effectively impedes the progression of ATM-mediated diseases and demonstrates significant anti-cancer activity. |
In vitro | Antitumor agent-28 effectively suppresses the activity of ataxia telangiectasia mutated (ATM; IC 50 =7.6 nM; HT29 cells) and ataxia telangiectasia and Rad3-related protein (ATR; IC 50 =18 μM; HT29 cells), as well as PI3Ka (IC 50 =0.24 μM; BT474 cells), showcasing its potential as a therapeutic option. Notably, it does not impact mTOR in MDA-MB-468 cells[1]. |
Molecular Weight | 512.63 |
Formula | C25H32N6O4S |
CAS No. | 2097499-67-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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